Peter Carmeliet

BfBio predicts angiogenic stalk cell genes using a Personalized PageRank algorithm, achieving high AUC-ROC performance and identifying novel cancer-related genes.

This study identifies Pfkfb3 as essential for astrocytic glycolysis, which preserves cognition by reducing mitochondrial efficiency and redirecting pyruvate to neurons.

This study investigates how hypernatremia affects action potential duration in a mouse model of long QT syndrome type 3, finding that it increases transient outward potassium currents and alters repolarization patterns.

This paper investigates VEGF supplementation as a treatment for congenital diaphragmatic hernia (CDH)-associated lung abnormalities using an ex vivo model and nanoparticle-based delivery in vivo.

This study shows GAS6 and AXL reduce insulin sensitivity by altering insulin signaling and increasing insulin receptor trafficking to endosomes.

This study shows that weak neuronal glycolysis supports cognition and organismal fitness by preventing mitochondrial redox stress and maintaining autophagy.

The paper constructs a molecular atlas of the human brain vasculature using single-cell RNA sequencing, revealing molecular heterogeneity and disease-related alterations in vascular cells.

This paper describes a method to image and analyze 3D vascular networks in mouse brains across development and adulthood, quantifying various vascular features.

The paper shows DNA methylation prevents HIF binding, affecting hypoxia responses and tumour immunotolerance.