Michael J. Petrany

This study identifies a multimodal transcriptional response in denervated skeletal muscle, revealing altered cholesterol homeostasis and its impact on myofiber size.

The paper identifies distinct transcriptional states of newly fused versus pre-existing nuclei in skeletal myofibers and shows their interplay in regulating muscle growth.

The paper identifies myomerger as a critical protein required for myoblast fusion and demonstrates its role in inducing fusogenicity in non-fusogenic cells.