Cristofer Calvo

This study uses single nucleus RNA sequencing to identify altered angiogenic signaling in JDM muscle, highlighting vascular and IFN pathways.

The paper shows that increasing RNA Polymerase II levels enhances mRNA content and drives myofiber growth without needing additional nuclei.

This study identifies a multimodal transcriptional response in denervated skeletal muscle, revealing altered cholesterol homeostasis and its impact on myofiber size.

The paper identifies distinct transcriptional states of newly fused versus pre-existing nuclei in skeletal myofibers and shows their interplay in regulating muscle growth.