Jia Guo

This paper develops a highly sensitive and multiplexed in situ protein profiling method using click chemistry and cleavable fluorophores, enabling the quantification of 28 proteins in FFPE tissue and classification of over 820,000 cells.

This paper introduces a highly sensitive in situ proteomics method using cleavable fluorescent tyramide and antibodies, enabling detailed analysis of protein expression in human tissues.

This paper introduces a method for highly sensitive and multiplexed in situ protein profiling using cleavable fluorescent streptavidin and biotin conjugated antibodies, achieving 10-fold improved sensitivity over existing methods.