Thai H. Pham

The paper develops an optimized multimodal imaging workflow that preserves tissue integrity and enables comprehensive profiling of morphology, collagen, cell populations, N-glycans, and extracellular matrix peptides from a single tissue section.

CelLink integrates single-cell multi-omics data by addressing weak feature linkage and imbalanced cell populations, outperforming existing methods in imputation accuracy and cell subtype annotation.

This paper introduces a multimodal pipeline for spatiomolecular analysis of tissue samples, demonstrating its application in Alzheimer's disease and type 2 diabetes.

The paper develops a multimodal imaging pipeline to identify molecular markers of cellular neighborhoods in human kidney tissue by integrating imaging mass spectrometry and immunofluorescence data.

This paper develops a highly sensitive and multiplexed in situ protein profiling method using click chemistry and cleavable fluorophores, enabling the quantification of 28 proteins in FFPE tissue and classification of over 820,000 cells.

This paper introduces a method for highly sensitive and multiplexed in situ protein profiling using cleavable fluorescent streptavidin and biotin conjugated antibodies, achieving 10-fold improved sensitivity over existing methods.