Author

Jake A. Ward

Institute for Research in BiomedicineORCID 0000-0001-8069-4839Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Afroditi SotiriouiD· 1 shared Ana BanitoiD· 1 shared Aneika C. LeneyiD· 1 shared Ashok Kumar JayaveluiD· 1 shared Beatriz Romartínez-AlonsoiD· 1 shared Bethany ThurairajahiD· 1 shared Bradley Robert CairnsiD· 1 shared Cristina Mayor‐RuiziD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Afroditi SotiriouORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 27, 2026

BAF complex-independent gene activation by SS18::SSX

Afroditi Sotiriou, Jinxiu Li, Sanya Middha…·Ana Banito

This study shows that SS18::SSX can drive transcription independently of BAF complex interaction and relies on EP300 for gene activation, suggesting new therapeutic targets for synovial sarcoma.

DOI 10.64898/2026.01.26.701739

humanexperimental assay

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BiochemistryJournal of Biological ChemistryPeer-reviewedJan 16, 2024

Characterising the Protein-Protein Interaction Between MDM2 and 14-3-3σ; Proof of Concept for Small Molecule Stabilisation

Jake A. Ward, Beatriz Romartínez-Alonso, Danielle F. Kay…·Richard G. Doveston

This paper characterises the phosphorylation-dependent interaction between 14-3-3σ and MDM2 and shows that small molecule stabilisation of this PPI is feasible using fusicoccin A.

14 citations

mouseproteomics

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