Jochen Huehn

This study maps DNA methylation patterns in human ILC subsets, identifies disease-linked regulators in ILC2, and shows their role in allergic inflammation.

This study shows that probiotic-modified microbiota from preterm infants reduces innate immune cell populations in mice and impairs bacterial clearance during infection.

This study identifies blood endothelial cells in secondary lymphoid organs as key APCs that prime donor CD4 T cells, leading to acute graft-versus-host disease.

This study shows that CREB knockout in Foxp3+ Tregs increases IL-10 and ST-2 expression, enhancing their suppressive function and preventing gut inflammation.

The paper examines the association between CMV-specific effector T cell subtypes, age, CMV serostatus, and systolic blood pressure in an elderly cohort.

The paper identifies TBKBP1 as a key gene whose demethylation enhances cytotoxic activity in CMV-specific CD8+ T cells, suggesting it as a therapeutic target.