Zhaowei Liu

This study uses optical tweezers to measure the mechanical properties of human centromeres, revealing stiffness at low forces and softening under tension, with implications for chromosome segregation.

This study shows how modifying anchor points on Anticalin scaffolds improves binding strength and adhesion to CTLA-4 under shear stress, enhancing targeted drug delivery.

The paper investigates how anchor point selection affects the mechanical stability of an Affibody/PD-L1 complex using multiple experimental and computational methods.

The paper demonstrates how modifying anchor geometry can generate catch bonding behavior in the DocG:CohE adhesion complex, showing mechanical anisotropy enables engineered catch bonds.

This paper introduces FUSION, a machine learning workflow for classifying and discovering protein unfolding trajectories from force spectroscopy data, achieving high accuracy and identifying new unfolding pathways.