Byeongseon Yang

The paper investigates the mechanical properties of the Izumo1:Juno complex using force spectroscopy and simulations, revealing its mechanostability and how mutations affect it.

This study investigates ADGRG1 activation mechanisms through mechanical and allosteric pathways, showing force direction determines signaling via GAIN domain dynamics and introducing engineered variants with tailored sensitivity.

The paper investigates how anchor point selection affects the mechanical stability of an Affibody/PD-L1 complex using multiple experimental and computational methods.

The paper develops an integrated method combining dynamic network analysis with AI to predict epitopes in PD-L1:Affibody interactions, showing the perpendicular binding mode is more stable.

The paper demonstrates how modifying anchor geometry can generate catch bonding behavior in the DocG:CohE adhesion complex, showing mechanical anisotropy enables engineered catch bonds.

This study investigates how fluorination affects the mechanical stability of a bacterial adhesion complex using single-molecule force spectroscopy, revealing distinct effects on equilibrium and non-equilibrium stability.