Jai Justin Tree

This study identifies two mechanisms of cefiderocol resistance in Acinetobacter baumannii: cAMP signalling disruption and Hfq RNA-binding domain truncation, both linked to iron homeostasis and reduced drug activity.

The paper shows that an RNA-RNA interaction within a bacterial operon represses SpoVG, affecting biofilm and cell wall properties in Staphylococcus aureus.

This study identifies two sRNAs in Staphylococcus aureus that regulate zinc homeostasis, showing their role in Zn-sparing responses and adaptation to metal limitation.

The paper identifies molecular features that distinguish functional from non-functional bacterial sRNA-mRNA interactions using integrative interactome and machine learning analysis.

The paper identifies an mRNA-binding motif recognized by the intrinsically disordered AR2 domain of RNase E, showing its role in substrate recognition and autoregulation.

The paper identifies a prophage-encoded sRNA, HnrS, that counteracts xenogenic silencing by repressing Hha, enabling virulence gene expression in E. coli.

The paper identifies sRNAs mediating translational repression in vancomycin-tolerant S. aureus, with RsaOI regulating HPr and Atl under cell wall stress.

The paper identifies Hfq-mediated sRNA-target interactions in E. coli that facilitate adaptation to nutrient availability changes.