Shadi Jafari

TRiXi detects X-inactivation skewing in human DNA, revealing it as a common and stable epigenetic trait across multiple tissues and ages.

The paper shows that in ants, orco mutations cause ORN apoptosis, but some ORNs survive by expressing Ir genes, suggesting chemosensory receptors mediate activity-dependent survival.

The paper shows that neuronal activity and stress during a critical period regulate olfactory receptor expression in Drosophila by modulating gene regulatory mechanisms.

The paper identifies a critical period in Drosophila olfactory sensory neuron differentiation that stabilizes odorant receptor expression through gene regulatory mechanisms similar to mammalian systems.