Author

Onur Boyman

University of ZurichORCID 0000-0001-8279-5545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Carmen S. M. Yong· 1 shared Diana TintoriD· 1 shared Irma TelarovićiD· 1 shared Jana Pachlopnik SchmidiD· 1 shared Lisa Gregor· 1 shared Martin N. PruschyiD· 1 shared Miro E. RaeberiD· 1 shared Samantha MilanesiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Carmen S. M. Yong

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2 papers

Recent·Most cited

ImmunologyiSciencePeer-reviewedMay 13, 2025

IL-2 immunotherapy rescues irradiation-induced T cell exhaustion in vivo

Carmen S. M. Yong, Irma Telarović, Lisa Gregor…·Onur Boyman

This study shows that timed CD25-biased IL-2 immunotherapy after RT enhances anti-tumor effects by promoting CD8+ T cell expansion and reducing exhaustion.

5 citations

mouseexperimental assay

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ImmunologybioRxivPreprintAug 12, 2024

Cytokine-Induced Cell Exhaustion to Mitigate Hyperinflammation

Tommaso Marchetti, Samantha Milanesi, Diana Tintor…·Jana Pachlopnik Schmid

This study shows that targeted IL-2 treatment reduces hyperinflammation in a perforin-deficient mouse model of HLH by inducing CD8+ T cell exhaustion.

DOI 10.1101/2024.08.12.607544

mouseexperimental assay

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