Ling Jing

This study identifies DNA methylation and gene expression changes in heart failure patients before and after LVAD therapy, linking extracellular matrix and cytoskeletal remodeling to myocardial recovery.

This study investigates the mechanisms of myocardial salvage in acute myocardial infarction using left ventricular unloading and reperfusion, identifying PPARG as a key cardioprotective gene and suggesting rosiglitazone as a potential adjuvant therapy.

This study shows that inhibiting MCT4 to redirect pyruvate metabolism reduces myocardial ischemia-reperfusion injury by improving mitochondrial function and reducing oxidative stress.

This study integrates clinical and transcriptomic data to predict myocardial recovery in heart failure patients after LVAD implantation, identifying 80 features with an AUC of 0.731.