Britta Eiz‐Vesper

The paper uses plasma immunopeptidomics guided by mutanomes to detect neoepitopes in solid tumors, finding that cfDNA variant calling sensitivity and MS detection limits constrain plasma-based detection.

This study compares T cell development in humanized mice with and without murine MHC, finding that busulfan conditioning in MHC-deficient mice promotes activated T cells while irradiation favors naive T cells.

This study develops next-generation CD30CAR-T cells using CRISPR/Cas9 for multiplex editing, showing high potency but risks of translocations with combined knockouts.

This paper develops ENTPD3-specific CAR Tregs to control T1D by targeting beta cells and shows their efficacy in preventing disease progression in a mouse model.

The paper identifies TBKBP1 as a key gene whose demethylation enhances cytotoxic activity in CMV-specific CD8+ T cells, suggesting it as a therapeutic target.