Author

Kira D. Leitl

Helmholtz MunichORCID 0000-0001-8438-7369Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Anne K. SchütziD· 1 shared Christos GatsogiannisiD· 1 shared Dierk NiessingiD· 1 shared Eri SakataiD· 1 shared Franz HagniD· 1 shared George BroutzakisiD· 1 shared Kai Fredriksson· 1 shared Manuel HitzenbergeriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Anne K. SchützORCID

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2 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedOct 27, 2025

Structural basis of apoptosis induction by the mitochondrial voltage dependent anion channel

Melina Daniilidis, Umut Günsel, George Broutzakis…·Franz Hagn

This study reveals how VDAC1 oligomerization triggers apoptosis by exposing its N-terminal helix, which neutralizes anti-apoptotic BclxL and promotes pore formation by Bak.

25 citationstop 2%

humanprotein structure

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BiophysicsNature ChemistryPeer-reviewedFeb 7, 2024

Unravelling ATP processing by the AAA+ protein p97 at the atomic level

Mikhail Shein, Manuel Hitzenberger, Tat Cheung Cheng…·Anne K. Schütz

This study uses cryo-EM, NMR, and MD simulations to reveal the atomic-level mechanism of ATP processing by p97, identifying a metastable ADP.Pi state and its role in coordinating subunit actions.

37 citationstop 4%

humancryo-EM

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