Author

Manuel Hitzenberger

Technical University of MunichORCID 0000-0001-9726-2370Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

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Anne K. SchütziD· 1 shared Eri SakataiD· 1 shared Kira D. LeitliD· 1 shared Martin ZachariasiD· 1 shared Mikhail Shein· 1 shared Smruti Ranjan RoutiD· 1 shared Tat Cheung ChengiD· 1 shared Yusuke SatoiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiophysics

Anne K. SchützORCID

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1 paper

Recent·Most cited

BiophysicsNature ChemistryPeer-reviewedFeb 7, 2024

Unravelling ATP processing by the AAA+ protein p97 at the atomic level

Mikhail Shein, Manuel Hitzenberger, Tat Cheung Cheng…·Anne K. Schütz

This study uses cryo-EM, NMR, and MD simulations to reveal the atomic-level mechanism of ATP processing by p97, identifying a metastable ADP.Pi state and its role in coordinating subunit actions.

37 citationstop 4%

humancryo-EM

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