Author

Tyler J. Smith

University of MichiganORCID 0000-0001-8444-6808Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Tyler J. Smith1 paper · University of California, San Francisco

Biology Disciplines

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Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Kristin S. KoutmouiD· 2 shared Anthony AntonellisiD· 1 shared Daniel E. EyleriD· 1 shared Garth A. NicholsoniD· 1 shared Joshua D. JonesiD· 1 shared Laura R. Snyder· 1 shared Marina L. KennersoniD· 1 shared Mehmet TarduiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Kristin S. KoutmouORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedAug 19, 2024

Conserved 5-methyluridine tRNA modification modulates ribosome translocation

Joshua D. Jones, Monika K. Franco, Rachel N. Giles…·Kristin S. Koutmou

This study identifies m5U54 as a conserved tRNA modification that modulates ribosome translocation and tRNA maturation.

25 citations

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GeneticsHuman Molecular GeneticsPeer-reviewedApr 3, 2023

A humanized yeast model reveals dominant-negative properties of neuropathy-associated alanyl-tRNA synthetase mutations

Rebecca Meyer‐Schuman, Sheila Marte, Tyler J. Smith…·Anthony Antonellis

The paper demonstrates that neuropathy-associated AARS1 mutations exhibit dominant-negative effects by reducing yeast growth when co-expressed with wild-type AARS1.

11 citations

yeastexperimental assay

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