Kristin S. Koutmou

The paper identifies 21 novel pseudouridine sites in S. cerevisiae tRNAs using DRS and BACS, and maps their modifying enzymes.

This study identifies bL27's role in preventing tmRNA from interfering with protein synthesis during trans-translation in bacteria.

The paper introduces tRNAZAP, a deep learning method using nanopore ionic current signals to classify tRNA isodecoders, achieving better alignment results than BWA-MEM in E. coli and S. cerevisiae.

The paper profiles RNA modifications in MS2 bacteriophage using LC-MS/MS and Nanopore DRS, finding {Psi} as the predominant modification.

This study identifies 17 rRNA methyltransferases in Bacillus subtilis, revealing their roles in ribosome function and antibiotic sensitivity through genetic and biochemical analyses.

This paper introduces a method using RNase 4 and HILIC-MS/MS to map tRNA modifications in E. coli with high coverage and without ion-pairing reagents.

This study investigates the role of DusA in tRNA modification and translation, finding it selectively enhances specific tRNA charging and translation at certain codons.

This study identifies TlyA as an rRNA methyltransferase critical for ribosome assembly in B. subtilis, showing its role in cold sensitivity and antibiotic resistance.

This study shows that PUS7's cytoplasmic localization enhances stress tolerance by increasing pseudouridylation of mRNAs involved in metal and ROS homeostasis.

The paper demonstrates that neuropathy-associated AARS1 mutations exhibit dominant-negative effects by reducing yeast growth when co-expressed with wild-type AARS1.