Olof Asplund

This study integrates multi-OMIC data from 12 cohorts to identify exercise-specific molecular signatures and gene regulatory patterns in human skeletal muscle.

This study identifies E2F1 and E2F8 as key regulators promoting cell proliferation, survival, and migration in pancreatic ductal adenocarcinoma.

This study shows exercise training reduces epigenetic and transcriptomic aging in human skeletal muscle, while muscle disuse accelerates transcriptomic aging.

The paper introduces Islet Gene View (IGW), a platform that integrates gene expression and phenotypic data from pancreatic islets to explore T2D-related gene expression changes and their functional implications.

This study identifies DIMT1 as a regulator of ribosomal biogenesis in beta-cells, showing its role in mitochondrial function and insulin secretion, with implications for type 2 diabetes.

The paper investigates how genetic variants affect gene expression in human pancreatic islets and identifies candidate genes linked to type 2 diabetes.