Guillaume Kraft

This study shows that morning insulin exposure enhances afternoon hepatic glucose disposal in dogs by increasing glucose-mediated mechanisms, though maximal effects also require elevated afternoon insulin.

This study investigates whether morning hyperglucagonemia affects the priming effects of morning hyperinsulinemia on subsequent hepatic glucose metabolism in dogs.

This study examines how glucagon affects hepatic glucose production and gene expression in conscious dogs over time, revealing transient metabolic flux changes and gene regulation patterns.

This study shows that a high-fat and fructose diet in dogs causes insulin resistance and β-cell dysfunction similar to human impaired glucose tolerance and type 2 diabetes.