José Antonio Escudero

The paper identifies Gfa, a new fosfomycin resistance protein family found in integrons, and shows it confers resistance across multiple bacterial species.

The paper introduces two tools to recover integron cassettes from bacterial genomes, identifying new phage-defense systems.

This study measures the fitness effects of 136 antimicrobial resistance genes in changing environments and finds that oxygen availability modulates their cost.

The paper identifies novel phage resistance systems encoded in mobile integrons and shows they can be combined for multi-phage and antibiotic resistance with variable fitness costs.

This study investigates how oxygen levels affect antimicrobial resistance gene performance in Enterobacterales, showing significant variations in resistance under aerobic and anaerobic conditions.

The paper shows that integron cassette expression depends on upstream translation rates, not distance to the Pc promoter.

The paper deletes a chromosomal integron in Vibrio cholerae and shows it has no detectable effect on physiology, proving its genetic and functional isolation.

The paper identifies promoter activity in gene-less cassettes from Vibrio superintegrons, showing they enhance downstream cassette expression and confer antibiotic resistance.