Filipa Trigo da Roza

The paper introduces two tools to recover integron cassettes from bacterial genomes, identifying new phage-defense systems.

The paper shows that integron cassette expression depends on upstream translation rates, not distance to the Pc promoter.

The paper deletes a chromosomal integron in Vibrio cholerae and shows it has no detectable effect on physiology, proving its genetic and functional isolation.

The paper identifies promoter activity in gene-less cassettes from Vibrio superintegrons, showing they enhance downstream cassette expression and confer antibiotic resistance.