Author

Helen Donelick

University of UtahORCID 0000-0001-8562-2260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Brenda BassiD· 2 shared Addison A. Young· 1 shared Adedeji M. AderounmuiD· 1 shared Claudia D. ConsalvoiD· 1 shared Debra M. Eckert· 1 shared Hung MaiiD· 1 shared Jackson R. PierceiD· 1 shared Jason D. WeberiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Brenda BassORCID

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2 papers

Recent·Most cited

Molecular BiologyScientific ReportsPeer-reviewedOct 9, 2024

Activation of PKR by a short-hairpin RNA

Kyle A. Cottrell, Sua Ryu, Helen Donelick…·Jason D. Weber

This study shows that an shRNA targeting DDX54 can activate PKR through a dsRNA-mediated mechanism, highlighting the need for careful validation of gene function.

5 citations

humanexperimental assay

𝕏 PostBluesky

BiochemistryeLifePeer-reviewedJan 17, 2024

C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA

Claudia D. Consalvo, Adedeji M. Aderounmu, Helen Donelick…·Brenda Bass

The paper investigates how C. elegans Dicer collaborates with DRH-1 and RDE-4 to cleave dsRNA, revealing their roles in antiviral defense mechanisms.

17 citations

C. elegansexperimental assay

𝕏 PostBluesky