Carsten Berndt

This study shows sodium aurothiomalate induces ferroptosis by covalently modifying GPX4 through a gold-dependent mechanism, leading to tumor growth reduction in preclinical models.

This study identifies fard-1 and dhs-25 as regulators of ferroptosis-driven aging in C. elegans by linking redox imbalance to oxidative stress and lifespan reduction.

This study shows SIRT1 limits neuronal fate after DNA damage by promoting repair and preventing damaged DNA from propagating to neurons.

This study examines how nephrotoxins and oxidants affect the differentiation and function of iPSC-derived renal proximal tubular cells, finding that differentiating cells are highly sensitive to these agents.

The paper shows PRDX6 influences ferroptosis sensitivity by managing cellular selenium levels, which affects GPX4 function.

This study shows oncogenic RAS signaling suppresses ferroptosis by upregulating GCH1 and BH4, making RAS-driven cancers resistant to ferroptosis-inducing agents.