Charles O. Rock

This study compares isoleucine regulation of IlvA in Escherichia coli and Staphylococcus aureus, revealing structural differences in their regulatory domains and feedback mechanisms.

This study identifies oleic acid as a compound that inhibits L. iners and promotes L. crispatus growth, offering a potential new treatment strategy for bacterial vaginosis.

This paper shows that the ytpAB operon, induced by cell wall inhibitors, helps Bacillus subtilis resist bacitracin by modulating membrane properties and interacting with resistance proteins.

This study identifies CoA metabolism dysregulation as a mechanism of resistance to HAT inhibitors in AML, revealing a potential class-wide vulnerability for anti-cancer therapies targeting HATs.