Author

Joseph R Rouse

Emory UniversityORCID 0000-0001-8675-904XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Allen C SteereiD· 1 shared Alyssa M. McLeland· 1 shared Amanda Wahhab· 1 shared Andrew L. RouthiD· 1 shared Angelica L. Morgan· 1 shared Brandon L JutrasiD· 1 shared Bryan A. JohnsoniD· 1 shared David Hughes WalkeriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Allen C SteereORCID

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2 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedDec 2, 2025

SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness.

Yiyang Zhou, Yani P. Ahearn, Kumari G. Lokugamage…·Vineet D. Menachery

This study shows SARS-CoV-2 NSP15 (EndoU) regulates RNA recombination and viral fitness, with its loss reducing replication but increasing inflammation and defective genomes.

13 citationstop 1%

humanbulk RNA-seq

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ImmunologybioRxivPreprintNov 21, 2023

HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis

Joseph R Rouse, Rebecca Danner, Amanda Wahhab…·Robert B Lochhead

This paper shows that HLA-DR-expressing fibroblast-like synoviocytes can present Lyme autoantigens and activate CD4+ T cells when stimulated with IFN-gamma and Borrelia burgdorferi.

DOI 10.1101/2023.11.21.568066

humanproteomics

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