Tuula A. Nyman

This study shows that carbon source determines metabolic states in Propionibacterium freudenreichii, affecting redox balance and vitamin B12 biosynthesis.

This study isolates plastids from Marchantia polymorpha and determines their proteome and high-resolution structures of chlororibosome and RuBisCO, revealing structural conservation and functional insights.

This study characterizes the proteomes of extracellular vesicles from 12 commensal bacterial species, revealing phylogenetic influences on protein composition and potential roles in host interactions.

This study benchmarks mass spectrometry-based antibody sequencing methods, revealing biases related to sequence, concentration, protease, and bioinformatics tools.

This study shows that errors in mitochondrial translation cause cellular stress and metabolic changes linked to disease and aging, independent of oxidative phosphorylation.

The paper shows that DDHD2-generated saturated fatty acids are essential for neuronal energy production and synaptic function.

This study identifies DOK2 and PTPN11 as novel interactors of TSAd using AP-MS, revealing their role in negative T cell signaling.

The paper develops a bioinformatic workflow to identify functional roles of less-understood proteins by analyzing scRNA-seq data, applying it to SH2D2A and linking it to T-T synapses enriched for ITGB2.

The paper identifies a COA5 missense variant causing isolated mitochondrial complex IV assembly impairment in two siblings and validates its role in early CIV assembly using patient-derived cells and CRISPR/Cas9 knockout models.

This study investigates how Propionibacterium freudenreichii adapts to aerobic conditions through transcriptomic and surfaceome analyses, revealing metabolic changes and growth responses.

This study benchmarks and integrates bulk and single-cell BCR sequencing with antibody peptide sequencing to understand the humoral immune response.

The paper investigates the functional roles of 14 unique human mitochondrial ribosomal proteins in the small subunit, showing their essentiality in assembly and translation, with a redox-regulated role for mS37.