Sachin Kumar Singh

This study benchmarks mass spectrometry-based antibody sequencing methods, revealing biases related to sequence, concentration, protease, and bioinformatics tools.

The paper develops a bioinformatic workflow to identify functional roles of less-understood proteins by analyzing scRNA-seq data, applying it to SH2D2A and linking it to T-T synapses enriched for ITGB2.

This study benchmarks and integrates bulk and single-cell BCR sequencing with antibody peptide sequencing to understand the humoral immune response.