Jacqueline E. Payton

This study shows that LAIR1 deficiency in mice leads to excessive inflammation during S. aureus infection, similar to CTCL, which increases tissue damage without improving infection control.

This study identifies and characterizes the NNLNS motif in Ebola virus VP35 that mediates MIB2 binding, inhibiting IFN production and affecting viral RNA synthesis.

This study shows ACLY supports NK cell effector functions by regulating glycolysis and histone acetylation, with acetate supplementation restoring these functions in ACLY-deficient cells.

This study tracks clonal evolution in cutaneous T-cell lymphoma using multi-omics data to identify progression-associated mutations and potential therapeutic targets.

The paper investigates how interferon signaling epigenetically regulates LAIR1 and LAIR2 expression in macrophages and T cells through transcriptional regulatory elements.

DXM deconvolves methylation profiles of subpopulations from heterogeneous bisulfite sequencing data, showing improved performance over existing methods and linking methylation to relapse in DLBCLs.