MicrobiologyProceedings of the National Academy of SciencesPeer-reviewed
SPATEs promote the survival of Shigella to the plasma complement system upon hemorrhage and bacteremia
Lorine Debande, Ahmad Sabbah, Lauriane Kühn…·Benoît Marteyn
This study shows Shigella survives plasma exposure via SPATEs, which cleave C3 to impair complement activation, enhancing virulence during bacteremia.