Lorine Debande

The paper investigates how human-targeted drugs alter regulatory networks in Salmonella Typhimurium, revealing non-antibiotic compounds reshape virulence and antibiotic resistance through specific transcriptional responses.

This study shows SigA forms amyloid fibrils that help Shigella sonnei compete with the microbiota by forming complexes with colicin E1 that have antimicrobial activity.

This study shows Shigella survives plasma exposure via SPATEs, which cleave C3 to impair complement activation, enhancing virulence during bacteremia.