Atsushi Shibata

This study uses Raman-Brillouin microscopy to show lipids are enriched in heterochromatin and influence its mechanical properties in living cells.

This study shows that hypomorphic Lig4 mutation in mice causes Th1-skewed intestinal inflammation under adaptive immunodeficiency.

This study shows SART1 promotes DSB end resection in HR, cooperates with BRCA1 to counteract 53BP1/RIF1, and is required for BRCA1 recruitment to DSBs.

This study identifies RAP80 as a suppressor of R-loop vulnerability during DNA double-strand break repair, preventing genomic abnormalities.