Author

Alexandra Prado-Mantilla

Duke Medical CenterORCID 0000-0001-8917-5904Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Terry LechleriD· 2 shared Wenxiu NingiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersGenetics

Terry LechlerORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 17, 2025

Spatio-Temporal Control of GFP-tagged Protein Degradation in the Mouse

Alexandra Prado-Mantilla, Terry Lechler

This paper introduces a system for spatial and temporal control of GFP-tagged protein degradation in mice, demonstrating its application to study the glucocorticoid receptor in the epidermis.

DOI 10.1101/2025.04.17.649420

mouseprotein structure

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJul 23, 2024

Molecular and Mechanical Signatures Contributing to Epidermal Differentiation and Barrier Formation

Alexandra Prado-Mantilla, Wenxiu Ning, Terry Lechler

The paper identifies molecular and mechanical features of intermediate and granular cells in epidermal development, showing contractility drives granular fate and barrier formation.

6 citations

mousebulk RNA-seq

𝕏 PostBluesky