Manfred Auer

The paper shows that DHRS7 loss increases nuclear size in prostate cancer cells and that estradiol propionate reduces nuclear size in DHRS7-lacking cells, suggesting DHRS7 as a biomarker for estrogen therapy effectiveness.

The paper introduces RP-CONA, a method to identify RNA-protein interaction modulators, and finds quercetin inhibits HuR-pri-miR-7-1 interaction, increasing miR-7 and reducing α-Synuclein.