Colinda L. G. J. Scheele

This study develops a method to generate functional mammary gland organoids from human induced pluripotent stem cells, showing they can form layered epithelium and respond to hormonal signals.

This study shows chemotherapy induces a Wnt-active diapause-DTP state in breast cancer cells, which can be targeted by combined Wnt and chemotherapy inhibition.

This study shows autophagy is essential for maintaining HEV function and expansion during inflammation, ensuring proper PNAd production and lymphocyte homing.

This study uses 3D imaging to analyze the structure and cell phenotypes of terminal ductal lobular units (TDLUs) in human breast tissue, revealing consistent branching patterns and new organizational features.

This study shows that autophagy in lymphatic endothelial cells controls T cell egress from lymph nodes, which is critical for immune checkpoint therapy effectiveness.