BiochemistryJournal of Molecular BiologyPeer-reviewed
Structure and methyl-lysine binding selectivity of the HUSH complex subunit MPP8
Nikos Nikolopoulos, Shun-ichiro Oda, Daniil M. Prigozhin, Yorgo Modis
This study reports the crystal structure of MPP8's C-terminal domain and its interaction with HUSH complex components, revealing its role in recruiting H3K9 methyltransferases to promote heterochromatinization.
10 citations