Oskar Gustafsson

This study investigates the role of tetraspanins in EV bioengineering by knocking out CD9, CD63, and CD81 in HEK293T cells and shows increased engineered EV production upon reintroduction of tetraspanin-fusion constructs.

This paper develops intein-engineered virus-like particles for efficient gene editing delivery, achieving robust gene editing in multiple cell types and organs.

This paper develops hPep peptide-based nanoparticles for systemic mRNA delivery, showing effective tissue distribution and protein expression in mice and non-human primates.

This paper develops hPep-based nanoparticles for efficient delivery of gene editors across multiple cell types, achieving high editing efficiency in human cells.

This study develops a method to accurately measure the elastic modulus of extracellular vesicles, showing that surface adhesion and membrane fluctuations significantly affect the results.

This study shows that SARS-CoV-2 and HSV-1 induce amyloid aggregation of proteins in human CSF, leading to soluble protein depletion, suggesting a potential mechanism linking viral infections to neurodegenerative diseases.