Lisa Shi Yun Li

This paper develops a homogenization approach to model cytokine diffusion and reaction dynamics in immune-cell environments, enabling efficient multiscale modeling by linking microscopic reaction-diffusion models to continuum approximations.

This study uses simulations to show that spatial cytokine inhomogeneities in T cell populations are critical for paracrine signaling and depend on cell population properties and feedback mechanisms.

The paper identifies genomic signatures predicting allopurinol and combination therapy responses in lung cancer using TCGA, CCLE, and patient-derived tumor data.

The paper shows that axonal transport of ins-6 mRNA helps C. elegans recover from stress, with opposing signals regulating this transport.