Hyopil Kim

DART automates aligning histological brain sections to 3D atlases and generates ROI contours for laser microdissection, improving precision and reproducibility in tissue sampling.

The paper introduces POINTseq, a method for cell type-specific single-cell projection mapping, and applies it to map 5,902 dopaminergic neurons, revealing over 25 connectomic cell types and stereotyped projection motifs.

MAPseq2 improves sensitivity and reduces cost for barcoded connectomics by enhancing the original MAPseq protocol.

This study shows that an autism-associated ASPM mutation causes macrocephaly and social-cognitive deficits in mice by altering the excitatory-inhibitory neuron ratio.

The paper investigates brain pH and lactate levels in animal models of neuropsychiatric disorders, finding decreased pH and increased lactate levels as common features across multiple models.

This study tracks synaptic changes in the hippocampus during fear memory formation and extinction, showing synaptogenesis and synapse modification between CA3 and CA1 engram cells.