ImmunologyCirculation ResearchPeer-reviewed
Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction
Chen Li, Sara K. Ture, Benjamín Nieves-López…·Craig N. Morrell
This study shows that thrombocytopenia causes monocyte immune dysfunction through platelet-monocyte CD47 interactions, leading to increased TLR responses and altered immunometabolism.