Author

Brian J. Bender

University of California, San FranciscoORCID 0000-0001-9251-9480Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Allan I. BasbaumiD· 1 shared Brennica MarlowiD· 1 shared Brian K. ShoichetiD· 1 shared Bryan L. RothiD· 1 shared Hye Jin KangiD· 1 shared Jens MeileriD· 1 shared João M. BráziD· 1 shared Julie E. PickettiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPharmacology & Toxicology

Allan I. BasbaumORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 25, 2023

Structure-Based Discovery of a NPFF1R Antagonist with Analgesic Activity

Brian J. Bender, Julie E. Pickett, João M. Bráz…·Brian K. Shoichet

This paper identifies a selective NPFF1R antagonist with analgesic properties, showing enhanced pain relief when combined with morphine and reduced side effects.

5 citations

mouseproteomics

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedOct 28, 2020

RosettaGPCR: Multiple Template Homology Modeling of GPCRs with Rosetta

Brian J. Bender, Brennica Marlow, Jens Meiler

This paper introduces a new Rosetta protocol for modeling GPCRs with improved accuracy, enabling modeling of nearly 90% of the GPCR family using low-identity templates.

44 citations

protein structurestatistical model

𝕏 PostBluesky