Kelsie L. Thu

This study shows that PD-L1 upregulation mediates resistance to CD47 inhibition in lung cancer, and dual inhibition of CD47 and PD-L1 improves survival in mouse models.

This study identifies CD47's role in promoting MAPK and EMT pathways to drive metastasis in NSCLC through cell-intrinsic signaling, independent of immune evasion.

This study identifies KIFC1 as a therapeutic vulnerability in lung cancers with centrosome amplification by showing its role in mitigating mitotic stress.

The paper identifies gene isoform-based biomarkers predictive of drug response in breast cancer using pharmacogenomic data from CCLE and GDSC.