Sophie Astrof

The study identifies 45 novel genes involved in palate development using IMPC knockout mouse embryos and micro-CT data.

This study identifies fibronectin as a key regulator of cardiac outflow tract elongation by modulating cell behavior in the second heart field.

The paper identifies a buffering mechanism in aortic arch artery development that compensates for reduced endothelial cell numbers, preventing congenital heart disease.

This study investigates SMAD4's role in cardiac neural crest cell survival, differentiation into vascular smooth muscle cells, and contribution to pharyngeal arch development using mouse models.

The paper identifies a novel site of late vasculogenesis in zebrafish embryos that contributes to functional blood vessels after circulation is established.

This study investigates how cell-ECM interactions, specifically through integrin 5β1 and fibronectin, regulate the morphogenesis of the aortic arch arteries at multiple developmental stages.

The paper identifies H2A.Z-dependent and -independent recruitment of metabolic enzymes to chromatin and shows their role in histone modifications in mouse heart cells.