Yasushi Hiraoka

The paper shows that proteasome-dependent removal of Orc6 from chromatin during S-phase prevents abnormal MCM reloading and tetraploidy in human cells.

The paper reconstructs artificial nuclei with nuclear import activity in living mouse oocytes using T4 phage DNA, showing they can form functional nuclear structures similar to natural nuclei.

This study identifies Bqt4 as an inner nuclear membrane protein that recruits phosphatidic acid to maintain nuclear envelope integrity in fission yeast.

This study investigates how RNA-protein condensates facilitate homologous chromosome pairing in meiosis by analyzing phase separation properties of sme2 RNA-associated proteins.

This study shows Lem2, an inner nuclear membrane protein in S. pombe, recruits exosome co-factors to the nuclear periphery to regulate RNA degradation and coordinate transcripts during the mitosis-to-meiosis switch.

The paper shows that different mutations at Gly 34 of histone H3 cause distinct phenotypes in cancer, affecting DNA repair and genomic stability.