Author

Yiyin Erin Chen

Broad InstituteORCID 0000-0001-9452-1402Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Aishan ZhaoiD· 1 shared Alessandra VeinbachsiD· 1 shared Alex DimasiD· 1 shared Amina Jbara· 1 shared Annalisa Hurd· 1 shared Arash Naziripour· 1 shared Brittany M. BerdyiD· 1 shared Caleb StaudingeriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

Aishan ZhaoORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 4, 2026

PSMε controls skin commensal CD8+ T cell activation

William S. Owens, Kevin Lenzi, Wendy Geng…·Yiyin Erin Chen

This study identifies PSMε as a key molecular component that drives CD8+ T cell activation by commensal bacteria, offering a mechanism for immunotherapy without live bacterial colonization.

DOI 10.64898/2026.07.30.741773

humanproteomics

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MicrobiologyNaturePeer-reviewedDec 11, 2024

Discovery and engineering of the antibody response against a prominent skin commensal

Djenet Bousbaine, Katherine D. Bauman, Yiyin Erin Chen…·Michael Andrew Fischbach

The paper identifies an antibody response against Staphylococcus epidermidis and shows how it can be engineered for therapeutic vaccination.

59 citationstop 1%

mousehuman

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