Author
University of California, Santa CruzORCID 0000-0001-9459-9154Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Rachel C. Harbeitner, Aidan C. Manning, Jonathan M. Howard…·Sergei A. Kazakov
The paper introduces RiboMarker, a method for comprehensive sRNA sequencing that detects all RNA fragment types, improving sensitivity for low-abundance biomarkers.
Jonathan M. Howard, Aidan C. Manning, Rachel C. Clark…·Sergio Barberán-Soler
This study characterizes transcriptomic changes in Coccidioides posadasii across different morphologies using RiboMarker-enhanced RNA sequencing, revealing small RNA and fragment expression patterns associated with life stage transitions.
Kejia Zhang, Aidan C. Manning, Jenna M. Lentini…·Dragony Fu
The paper identifies the roles of TRMT1 and TRMT1L in tRNA modifications, showing their impact on tRNA stability and function, and links TRMT1 variants to disease.
Andrew Holmes, Jonathan M. Howard, Patricia P. Chan, Todd M. Lowe
tRAX is a tool for analyzing tRNAs and tRNA-derived small RNAs, demonstrating its effectiveness in characterizing these transcriptomes in mouse tissues.
Bryan P. Thornlow, Joel C. Armstrong, Andrew Holmes…·Todd M. Lowe
The paper predicts tRNA gene activity using sequence and genomic context features, finding strong correlations with G+C content and CpG density.
Jonathan M. Howard, Hai Lin, Andrew J. Wallace…·Jeremy R. Sanford
The paper investigates how HNRNPA1 influences U2AF2 RNA binding in vivo, showing it shifts U2AF2 to decoy splice site sequences and affects exon skipping.