Glutamine-driven mTORC1 activity enforces glycolytic bias, hyperactivation and aberrant proliferation in T cells in chronic B-cell leukemia
Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet…·Helga Simon‐Molas
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Leiden UniversityORCID 0000-0001-9498-2620Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet…·Helga Simon‐Molas
Marouba Cisse, Wesley Huisman, Youvika Singh…·Simon P. Jochems
This study maps SES-related immune diversity using flow cytometry, finding lower SES associates with downregulated surface proteins and upregulated immune checkpoints.
Jelle G. Schipper, Chiara Aloise, Sereina O. Sutter…·Frank J. M. van Kuppeveld
This study demonstrates that enterovirus 2A protease is critical for viral replication and evasion of host antiviral responses through multiple mechanisms.
Frank Vrieling, Hendrik J.P. van der Zande, Britta Naus…·Rinke Stienstra
The paper introduces CENCAT, a method to measure protein synthesis inhibition in immune cells using noncanonical amino acid tagging, showing its utility in analyzing metabolic responses in complex samples and tissue-resident immune cells.
Joep Joosten, Bob van Sluijs, Wilma Vree Egberts…·Evan Spruijt
This study investigates how varying ratios of HspB2 and HspB3 affect their phase behavior, revealing reversible condensates and aggregates with distinct molecular compositions.