Filip Scheperjans

This study shows that stool-derived extracellular vesicles from Parkinson's disease patients have alpha-synuclein seeding activity detectable by seed amplification assay, with improved sensitivity after pre-incubation with recombinant monomeric alpha-synuclein.

This study compares plasmid and phage populations in gut microbiota of Parkinson's disease patients and healthy controls, finding significant differences in diversity and using machine learning to classify subjects with high accuracy.

The paper constructs metagenome-assembled genomes from fecal samples of Parkinson's disease and control groups, identifying microbial diversity and gene differences between the groups.

The paper investigates associations between gut microbiome composition and risk/prodromal markers of Parkinson's disease in elderly participants.