Author
University of DundeeORCID 0000-0001-9512-3828Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
Irene Georgiou, Sandra O’Neill, Colin Robinson…·Duncan E. Scott
The paper investigates false positives in SARS-CoV-2 nsp3 protease HTS assays caused by metal contamination and identifies copper and palladium as primary contaminants.
Ryan Wallis, Bethany K. Hughes, Madeleine Moore…·Cleo L. Bishop
SAMP-Score identifies pro-senescence compounds in Sen-Mark+ cancers by classifying senescence based on morphology, leading to the discovery of QM5928.
Janine L. Gray, Elizabeth V. K. Ledger, Tiffany Suwatthee…·Edward W. Tate
The paper identifies IMP-2380, a potent NorA inhibitor that enhances antibiotic activity by stabilizing the outward-open conformation of the efflux pump.
Lesley-Anne Pearson, Alain‐Pierre Petit, César Mendoza-Martínez…·David W. Gray
This study characterizes small molecule inhibitors of the HsRNMT-RAM complex, showing competitive binding and uncompetitive inhibition of RNA cap methylation.
Stuart Lang, Daniel A. Fletcher, Alain‐Pierre Petit…·David W. Gray
The paper uses NMR and crystallography to identify and assess new HIV-CA binding fragments, leading to the discovery of two compounds with improved binding properties.
Stuart Lang, Fiona Bellany, De Lin…·Fraser Cunningham
The paper identifies PAINS in a USP8 inhibitor screening campaign for Parkinson's disease and discusses interference mechanisms affecting assay reliability.