Manuela Helmer‐Citterich

The paper uses whole genome sequencing to analyze the genetic structure of a Greek-speaking community in Southern Italy, finding no strong evidence for external origins and supporting a model of continuous gene flow.

The paper introduces CORAL, a deep learning framework for RNA-protein interaction prediction that improves generalization and interpretability through cross-attention mechanisms.

The paper integrates transcriptomic data from 10 autoimmune diseases to identify core immune mechanisms and disease-specific signatures, revealing shared and distinct immunopathological patterns through 15 immune modules.

The paper identifies conserved modular exonic regions in human lncRNAs, showing evidence of purifying selection and suggesting functional units similar to protein-coding genes.

The paper identifies conserved paralog substitutions during neuronal differentiation across species and shows their impact on neuron development.

COTAN estimates gene co-expression in scRNA-seq data to analyze cell identity factors and infer gene interactomes.

The paper identifies miR-541 as an Eutherian-specific microRNA that regulates Satb2 translation during cortical development, revealing its role in timing neuronal identity.